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KMID : 0869420200180010047
Journal of Jeahan Oriental Medical Academy
2020 Volume.18 No. 1 p.47 ~ p.50
A review of acupuncture effects on alcohol dependence-induced anxiety-like behavior
Jeong Eun-Young

Yang Chae-Ha
Kim Hee-Young
Abstract
Objective : Previous studies have shown that acupuncture suppresses anxiety-like behavior and ethanol self-administration following chronic ethanol exposure. The present manuscript explores studies directed at elucidating the neural circuit and brain regions for acupuncture control of anxiety-like behavior associated with ethanol dependence.

Methods : This review summarized the possible neural circuit related to the application of acupuncture for anxiety-like behavior in ethanol dependence by searching research and review articles through the keywords ¡®acupuncture, ethanol dependence, anxiety, infralimbic cortex, central amygdala¡¯ on Pubmed, google scholar and RISS sites.

Results and conclusion : Neuropharmacological studies of ethanol dependence suggest important roles for GABA, endorphin, and glutamate in acupuncture-mediated inhibition of anxiety-like behavior. Studies of ethanol dependence have implicated neural circuit including prefrontal cortex and central amygdala in acupuncture effects on anxiety-like behavior in dependent animals.
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